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NFL PicksNovember 10, 2025

NFL Week 11 Picks - Sunday's Best Bets

Betbook AI6 min read
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NFL Week 11 Picks - Sunday's Best Bets


Game of the Week: Chiefs vs Bills


Pick: Over 47.5

Confidence: High


This AFC championship rematch features two of the league's best offenses. Patrick Mahomes and Josh Allen are both playing at MVP levels.


Key Stats:

  • Last 3 meetings averaged 58 points
  • Chiefs averaging 31 PPG this season
  • Bills allowing 28+ points in 4 of last 6 games

  • More Top Picks


    Cowboys vs 49ers

    Pick: 49ers -7


    The Cowboys are dealing with multiple injuries on defense, and the 49ers are 6-1 ATS at home this season.


    Packers vs Vikings

    Pick: Packers ML


    Jordan Love has been lights out in cold weather games, and the Vikings have lost 3 straight on the road.




    Betting Tips for NFL Week 11


    1. **Weather Matters:** Check forecast for outdoor games

    2. **Injury Reports:** Monitor practice reports through Saturday

    3. **Line Movement:** Sharp bettors move lines early in the week




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    NFL Week 11 Picks - Sunday's Best Bets | Betbook Blog