NFL Week 11 Picks - Sunday's Best Bets

Game of the Week: Chiefs vs Bills

Pick: Over 47.5

Confidence: High

This AFC championship rematch features two of the league's best offenses. Patrick Mahomes and Josh Allen are both playing at MVP levels.

Key Stats:

Last 3 meetings averaged 58 points

Chiefs averaging 31 PPG this season

Bills allowing 28+ points in 4 of last 6 games

Pick: 49ers -7

The Cowboys are dealing with multiple injuries on defense, and the 49ers are 6-1 ATS at home this season.

Pick: Packers ML

Jordan Love has been lights out in cold weather games, and the Vikings have lost 3 straight on the road.

1. **Weather Matters:** Check forecast for outdoor games

2. **Injury Reports:** Monitor practice reports through Saturday

3. **Line Movement:** Sharp bettors move lines early in the week

[Get all our NFL picks →](https://betbook.app/auth/login)